Case 04 / AI-assisted research
GLP-1 / NUTRITIONAL SUPPORT

GLP-1 and nutrition.
From question to dossier.

What can AI produce when research starts with a precise question? An example to read, check and download.

Download the complete researchPDF · 8 pages · 108 KB · English document
Inside the document.
08Pages10ReferencesIT / ENTwo editions
Preview of the downloadable document: GLP-1 therapies and nutritional support.
PDF / 01Preview of the downloadable document
01 / THE BRIEF

The question comes before the search.

What human evidence supports nutrition during GLP-1-based treatment, and which conclusions still need dedicated studies?

The intended reader works in R&D or scientific marketing. The aim is to navigate clinical findings, nutritional priorities and studies still to be completed.

PDF / 8 PAGES

Inside the document.

Three pages from the actual PDF: synthesis, data and method. Open a preview to read it at full size.

GMA / AI LAB

Dossier preview

The synthesis
A FIRST READING

Three findings from the reading.

The sources answer different questions. The dossier preserves that distinction through to its conclusion.

01

Lean mass needs a precise reading.

Weight, fat mass and lean mass all fell in the SURMOUNT-1 DXA substudy. They are different measures, each relative to its own baseline. DXA does not measure muscle alone, and the trial does not test a protein supplement. [S01]

02

The intervention context matters.

A trial combining exercise and liraglutide supports studying combined programmes. Its findings belong to that medicine, training programme and population; they do not establish the effect of a nutraceutical formulation. [S02]

03

New questions have dedicated studies.

LEAN-PREP plans to study protein and exercise; VITAGLP a multivitamin. In the documents consulted, the former is a protocol and the latter a registration with no posted results. Design, planned enrolment and observed outcomes must remain distinct. [S04, S05]

HOW IT WAS MADE

From research to checking.

AI assisted research across sources, evidence organisation and drafting. Editorial checks traced numbers, samples, comparators and study status back to the original documents.

  1. 01Define the question
  2. 02Search and connect
  3. 03Check the sources
  4. 04Deliver the dossier

Research conducted in Codex on 24 October 2026, with web consultation and original-source checks. A targeted synthesis, not a systematic review or independent clinical validation.

A prompt for repeating the approach

A reusable template drawn from this case’s brief and checks. Adapt the question, audience and date; always check the output against the sources.

REUSABLE BRIEF / GMA AI LAB

Question: What human evidence supports nutrition during GLP-1-based treatment, and which conclusions still need dedicated studies?

Readers: R&D and scientific marketing. Search cut-off: 24 October 2026 (update it when repeating the work).

Find original human studies, relevant consensus documents and registrations. Retain author, title, date, DOI or identifier and link. State whether you read the abstract or full text.

For each study extract population, planned and analysed sample, intervention, comparator, duration, measure and outcome. Distinguish lean mass, muscle and function; retain uncertainty, negative findings, funding and limitations. Check corrections. Do not treat protocols or registrations as findings, or add samples from related studies.

Prepare a readable synthesis with an evidence matrix, open questions and bibliography. Separate source conclusions from proposed research. Check references, numbers and wording before using the document.

This is a reusable template, not a conversation log or a guarantee of identical output.
Download the prompt · TXT
SOURCE LEDGER

The sources remain within reach.

The PDF contains all ten references. Here you can open the five selected studies and the sources supporting the method.

  1. S01Clinical substudy · results · 2025Look et al. · SURMOUNT-1 DXA
  2. S02Clinical trial · results · 2021Lundgren et al. · exercise and liraglutide
  3. S03Follow-up of the same trial · 2024Jensen et al. · post-treatment follow-up
  4. S04Protocol · results unavailable · 2026LEAN-PREP · protocol
  5. S05Registration · no results posted · 2025; checked 2026VITAGLP · NCT07234916
  6. S06Joint advisory · 2025; with 2026 corrigendumMozaffarian et al. · joint advisory
  7. S07Correction · 23 April 2026 · 23 April 2026Obesity · corrigendum
  8. S08Expert consensus · online 11 November 2025; March 2026 issueSievenpiper et al. · Delphi consensus
  9. S09Institutional document · 1 December 2025WHO · obesity and GLP-1 therapies
  10. S10Figure correction · 20 August 2025SURMOUNT-1 · figure correction
GMA / AI LAB

GLP-1 therapies and nutritional support.

PDF · 8 pages · 108 KB · 10 references · 24 October 2026

Download the complete research

An editorial example for professionals. Statements and data describe selected sources; they are neither prescriptions nor finished-product claims.

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